979-32 Endothelial-derived Relaxing Factor (Nitric Oxide) Has a Tonic Vasodilating Action on Coronary Collateral Vessels
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چکیده
منابع مشابه
The Possible Involvement of Nitric Oxide/Endothelium Derived Relaxing Factor in Atropine-Induced Vasorelaxation
Atropine has been used to block cholinergic neurotransmission in basic research. Large doses of atropine cause vasodilation of the blood vessels in the skin. This effect is apparently unconnected with the antimuscarinic activity of atropine and seems to be due to a direct action on the blood vessels. It has been suggested that atropine blocks muscarinic receptors at low doses and it induces th...
متن کاملEndothelium-derived relaxing factor in brain blood vessels is not nitric oxide.
BACKGROUND The endothelium-derived relaxing factor that mediates the actions of acetylcholine is now most frequently identified as nitric oxide. Nitric oxide is believed to have numerous important regulating actions in neurons, blood vessels, and several other biological systems. SUMMARY OF REVIEW The literature concerning tissue other than cerebral blood vessels supports the conclusion that ...
متن کاملComments, Opinions, and Reviews Endothelium-Derived Relaxing Factor in Brain Blood Vessels Is Not Nitric Oxide
Background: The endothelium-derived relaxing factor that mediates the actions of acetylcholine is now most frequently identified as nitric oxide. Nitric oxide is believed to have numerous important regulating actions in neurons, blood vessels, and several other biological systems. Summary of Review: The literature concerning tissue other than cerebral blood vessels supports the conclusion that ...
متن کاملIschemia-induced coronary collateral growth is dependent on vascular endothelial growth factor and nitric oxide.
BACKGROUND We hypothesized that ischemia-induced expression of vascular endothelial growth factor (VEGF) and the production of NO stimulate coronary collateral growth. METHODS AND RESULTS To test this hypothesis, we measured coronary collateral blood flow and VEGF expression in myocardial interstitial fluid in a canine model of repetitive myocardial ischemia under control conditions and durin...
متن کاملThe identification of nitric oxide as endothelium-derived relaxing factor.
The identification of endothelium-derived relaxing factor as nitric oxide (NO) dramatically altered the course of vascular biology, as well as other biomedical disciplines. The ubiquity of this natural product of cell metabolism and the complexity of its biochemistry provide a rich source of molecular mediators of phenotype in health and disease.
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ژورنال
عنوان ژورنال: Journal of the American College of Cardiology
سال: 1995
ISSN: 0735-1097
DOI: 10.1016/0735-1097(95)92542-d